SCHEMBL11047177

SCHEMBL11047177

CCCCCC1(Cn2ccnc2)SCC(C)CS1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 3/20 0.44
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
HMOX1 P09601 2/20 0.34
PRKCI P41743 1/20 0.32
QPCT Q16769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781903 0.99 TBXAS1 (0.47) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL11041699 0.99 TBXAS1 (0.47) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL11045644 0.99 TBXAS1 (0.47) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL11044530 0.99 TBXAS1 (0.47) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL11043302 0.99 TBXAS1 (0.47) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL11041471 0.91 CYP11B1 (0.41) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL10780585 0.88 TBXAS1 (0.43) TBXAS1CYP11B1CYP11B2HMOX1PRKCI
SCHEMBL10784933 0.87 TBXAS1 (0.46) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL10779868 0.87 TBXAS1 (0.46) TBXAS1CYP11B1CYP11B2HMOX1
SCHEMBL10781022 0.87 TBXAS1 (0.52) TBXAS1PRKCIQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4489087-A Spermicidal thioketal substituted N-alkyl imidazoles SYNTEX (U.S.A.) INC. (US) 1984-12-18 US disclosed