Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.60 |
| ▸ | POLB | P06746 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12580051 | 0.81 | ALDH1A1 (0.65) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL13362134 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL10410638 | 0.77 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL10245401 | 0.77 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTTDP1HPGD | |
| Hydrochloric Acid SCHEMBL10410636 | 0.76 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL6130008 | 0.75 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL21397712 | 0.74 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL140950 | 0.74 | TSHR (0.59) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL24060791 | 0.73 | CHRM2 (0.48) | ALDH1A1POLBMAPTTDP1MAPK1 | |
| SCHEMBL4869503 | 0.73 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431802-A | N-Heterocyclyl-N-cyano-N-(heterocyclythioalkyl)-guanidines | G. D. SEARLE & CO. (US) | 1984-02-14 | — | — | US | disclosed |