Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042030 | 0.95 | MAPK1 (0.35) | MAPK1MAOAMAOB | |
| SCHEMBL137566 | 0.91 | MAPK1 (0.34) | MAPK1MAOAMAOB | |
| SCHEMBL28460876 | 0.81 | MAOA (0.32) | MAPK1MAOAMAOB | |
| SCHEMBL2136195 | 0.80 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL3344922 | 0.79 | MAPK1 (0.33) | MAPK1MAOAMAOB | |
| SCHEMBL297459 | 0.79 | MAPK1 (0.33) | MAPK1MAOAMAOB | |
| SCHEMBL11075927 | 0.78 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL2138060 | 0.78 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL11043481 | 0.77 | MAOA (0.36) | MAPK1MAOAMAOB | |
| SCHEMBL20222460 | 0.75 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115531-A1 | SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM | POLYMATIC INVESTMENT CORPORATION N.V. (AN) | 1984-08-15 | — | — | EP | disclosed |
| US-4450264-A | CROSSLINKED COPOLYMER OF A TRIS/TRIMETHYLSILOXY/SILYL ALKYL OR CYCLOHEXYL ACRYLATE; OXYGEN PERMEABILITY | POLYMATIC INVESTMENT CORP., N.V. (NL) | 1984-05-22 | — | — | US | disclosed |
| WO-1984000763-A1 | SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM | POLYMATIC INVESTMENT CORP NV (NL) | 1984-03-01 | — | — | WO | disclosed |