SCHEMBL3344922

SCHEMBL3344922

CO[Si](C)(CCC1CC=CCC1)OC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CDK1 P06493 2/20 0.31
CCNB1 P14635 2/20 0.31
CCNA2 P20248 2/20 0.31
CDK2 P24941 2/20 0.31
CCNA1 P78396 2/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297459 0.86 MAPK1 (0.33) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL28460876 0.84 MAOA (0.32) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL137566 0.84 MAPK1 (0.34) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL3341005 0.83 MAPK1 (0.32) MAPK1MAOAMAOBKDM4EALDH1A1
SCHEMBL295809 0.81 MAOA (0.33) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL11042030 0.81 MAPK1 (0.35) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL9188733 0.80 MAPK1 (0.34) MAPK1MAOAMAOBCDK1CCNB1
SCHEMBL11041752 0.79 MAPK1 (0.35) MAPK1MAOAMAOB
SCHEMBL20222460 0.78 KDM4E (0.32) KDM4EALDH1A1PKM
SCHEMBL12212529 0.78 KDM4E (0.34) MAPK1MAOAMAOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
CN-111607089-B Functional polyhydrosilsesquioxane resin compositions, methods of producing the same, and uses thereof 彼博股份有限公司 2023-10-10 CN disclosed
US-20220162391-A1 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2022-05-26 US disclosed
CN-111607089-A Functional polyhydrosilsesquioxane resin compositions, methods of producing the same, and uses thereof 彼博股份有限公司 2020-09-01 CN disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed
US-4450264-A CROSSLINKED COPOLYMER OF A TRIS/TRIMETHYLSILOXY/SILYL ALKYL OR CYCLOHEXYL ACRYLATE; OXYGEN PERMEABILITY POLYMATIC INVESTMENT CORP., N.V. (NL) 1984-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 MAPK1 2966/4885MAOA 4610/4885MAOB 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.