Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728494 | 0.77 | CALM1 (0.38) | CALM1SIGMAR1TAAR1MAOA | |
| SCHEMBL30783418 | 0.74 | SIGMAR1 (0.30) | NPC1RAB9ASIGMAR1MEN1KMT2A | |
| SCHEMBL28060781 | 0.69 | NPC1 (0.36) | NPC1RAB9ASIGMAR1MEN1KMT2A | |
| SCHEMBL5229204 | 0.67 | NPC1 (0.38) | NPC1RAB9ASIGMAR1MEN1KMT2A | |
| SCHEMBL2836936 | 0.62 | CALM1 (0.46) | CALM1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL5227564 | 0.62 | SLC6A2 (0.48) | CALM1SIGMAR1DRD4HTR1ADRD2 | |
| SCHEMBL30403808 | 0.61 | SIGMAR1 (0.41) | HPGDSIGMAR1MEN1KMT2ACTSG | |
| SCHEMBL9143779 | 0.61 | CALM1 (0.44) | CALM1SIGMAR1TAAR1 | |
| SCHEMBL9144956 | 0.61 | CALM1 (0.44) | CALM1SIGMAR1TAAR1 | |
| SCHEMBL1903814 | 0.60 | CALM1 (0.38) | CALM1ALDH1A1HPGDSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436819-A | QUANTIFYING, WITH COLOR CHANGE UPON REACTION | ASSAY TEC ASSOCIATES, INC. (US) | 1984-03-13 | — | — | US | claimed |
| US-4436819-A | QUANTIFYING, WITH COLOR CHANGE UPON REACTION | ASSAY TEC ASSOCIATES, INC. (US) | 1984-03-13 | — | — | US | disclosed |