Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737227 | 0.86 | ERN1 (0.57) | ERN1SRCALDH1A1KDM4ETSHR | |
| SCHEMBL29951095 | 0.82 | ERN1 (0.52) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL1186103 | 0.82 | ERN1 (0.52) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL7522554 | 0.80 | ERN1 (0.52) | ERN1SRCALDH1A1KDM4ETSHR | |
| SCHEMBL31166894 | 0.80 | ALDH1A1 (0.42) | ERN1SRCALDH1A1KDM4ETSHR | |
| SCHEMBL4599553 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL30673247 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL3664240 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL130227 | 0.79 | ACHE (0.52) | ALDH1A1KDM4ETDP1ACHEMEN1 | |
| SCHEMBL18393631 | 0.78 | ALDH1A1 (0.41) | ERN1SRCALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |