Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OGT | O15294 | 1/20 | 0.32 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253228 | 0.76 | NOS1 (0.49) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL31139539 | 0.76 | NOS1 (0.49) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL11043657 | 0.75 | KMO (0.34) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL5732582 | 0.74 | POLB (0.38) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL11163899 | 0.72 | CYP1A2 (0.37) | KMOCYP1A2TSHR | |
| SCHEMBL11040319 | 0.71 | KMO (0.34) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL1250234 | 0.68 | PSMB8 (0.61) | NOS1NOS3NOS2LMNACYP1A2 | |
| SCHEMBL11334635 | 0.67 | NOS1 (0.42) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL11041742 | 0.67 | F2 (0.49) | NOS1NOS3NOS2LMNACYP1A2 | |
| SCHEMBL18062718 | 0.66 | KMO (0.35) | KMONOS1NOS3NOS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045892-B1 | PROCESS FOR THE PREPARATION OF PRECURSORS FOR POLYMERS CONTAINING THE OXAZOLIN-2-ONE RING, AND THEIR USE IN THE PRODUCTION OF HIGH MOLECULAR WEIGHT POLYMERS | BAYER AG (DE) | 1984-02-01 | — | — | EP | disclosed |
| EP-0050780-B1 | ISOCYANATO-OXAZOLINONES, METHOD FOR THE PREPARATION OF OXAZOLIDIN-2-ONE RINGS CONTAINING PLASTICS PRECURSORS, AND THEIR USE IN THE PREPARATION OF HIGH-MOLECULAR PLASTICS | BAYER AG (DE) | 1983-12-28 | — | — | EP | disclosed |
| US-4350781-A | Process for the preparation of polymer precursors containing oxazolin-2-one rings | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0050780-A1 | Isocyanato-oxazolinones, method for the preparation of oxazolidin-2-one rings containing plastics precursors, and their use in the preparation of high-molecular plastics | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0045892-A1 | Process for the preparation of precursors for polymers containing the oxazolin-2-one ring, and their use in the production of high molecular weight polymers | BAYER AG (DE) | 1982-02-17 | — | — | EP | disclosed |