Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642404 | 0.80 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL20764854 | 0.79 | IDO1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL27774487 | 0.79 | IDO1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL28741804 | 0.79 | ALDH1A1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL11138739 | 0.79 | ALDH1A1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL28256417 | 0.79 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPK1MBTD1 | |
| SCHEMBL29013797 | 0.78 | IDO1 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL16954438 | 0.77 | IDO1 (0.43) | IDO1TDO2ALDH1A1MAPK1MBTD1 | |
| SCHEMBL27917252 | 0.77 | IDO1 (0.43) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL4082761 | 0.77 | IDO1 (0.50) | IDO1TDO2ALDH1A1MAPK1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474999-A | Phenol compounds, process and polymers | GENERAL ELECTRIC COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| US-4415724-A | Branched aromatic polycarbonate from tetraphenol | GENERAL ELECTRIC COMPANY (US) | 1983-11-15 | — | — | US | disclosed |