SCHEMBL11042151

SCHEMBL11042151

COc1cccc(N=C=O)c1SC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 3/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA4 P22748 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
DAO P14920 1/20 0.33
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471398 0.78 ALDH1A1 (0.61) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL77114 0.78 ALDH1A1 (0.61) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL2169591 0.77 CYP3A4 (0.52) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL1332133 0.77 CYP3A4 (0.57) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL4726617 0.77 CYP3A4 (0.68) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL30438740 0.77 CYP3A4 (0.57) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL3548169 0.76 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL1899849 0.76 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1GABRA1
SCHEMBL4056709 0.76 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL3399416 0.76 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4514210-A Herbicidally active methyl-substituted tetrahydro-2-pyrimidinone derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-04-30 US disclosed