Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471398 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL9795424 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL7529762 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL8943270 | 0.84 | CYP3A4 (0.50) | ALDH1A1TDP1CYP3A4HPGDKMT2A | |
| SCHEMBL29031306 | 0.83 | CYP3A4 (0.45) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL1417851 | 0.83 | CA1 (0.52) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL29369823 | 0.83 | CYP3A4 (0.50) | ALDH1A1TDP1CYP3A4HPGDTSHR | |
| SCHEMBL1356140 | 0.83 | CYP3A4 (0.50) | ALDH1A1TDP1CYP3A4HPGDTSHR | |
| SCHEMBL1332133 | 0.82 | CYP3A4 (0.57) | ALDH1A1TDP1CYP3A4HPGDCA1 | |
| SCHEMBL4726617 | 0.82 | CYP3A4 (0.68) | ALDH1A1TDP1CYP3A4HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| CN-118271131-B | Self-repairing modified lignin-based polyester polyol coating material and preparation method thereof | 山东农业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-118271131-A | Self-repairing modified lignin-based polyester polyol coating material and preparation method thereof | 山东农业大学 | 2024-07-02 | — | — | CN | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| CN-114195671-B | Asymmetric malonyl aniline compound and synthesis method thereof | 河南师范大学 | 2023-09-22 | — | — | CN | claimed |
| CN-116525948-A | Method for inhibiting corrosion of aluminum foil of lithium battery current collector based on isocyanate additive | 临沂大学 | 2023-08-01 | — | — | CN | claimed |
| CN-115385973-B | Application of oligonucleotide-tetrahydrothiazole compounds in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2023-06-06 | — | — | CN | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| CN-115385973-A | Application of oligo-nucleic acid-thiazolidine compound in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-114195671-A | Asymmetric malonanilide compound and synthesis method thereof | 河南师范大学 | 2022-03-18 | — | — | CN | claimed |
| US-20070123642-A1 | Phase change inks containing curable isocyanate-derived compounds | XEROX CORPORATION | 2007-05-31 | — | — | US | claimed |
| US-20070120909-A1 | Phase change inks containing curable isocyanate-derived compounds and phase change inducing components | XEROX CORPORATION | 2007-05-31 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-1370910-A4 | THERMOSETTING ANTI-REFLECTIVE COATINGS COMPRISING ARYL URETHANES OF HYDROXYPROPYL CELLULOSE | BREWER SCIENCE INC (US) | 2004-09-15 | — | — | EP | claimed |
| EP-1370910-A1 | THERMOSETTING ANTI-REFLECTIVE COATINGS COMPRISING ARYL URETHANES OF HYDROXYPROPYL CELLULOSE | Brewer Science, Inc. (US) | 2003-12-17 | — | — | EP | claimed |
| US-6576408-B2 | Made by reacting a hydroxyalkyl cellulose with an aryl isocyanate such as phenyl isocyanate; coatings have high etch rate and optical density | BREWER SCIENCE, INC. | 2003-06-10 | — | — | US | claimed |
| WO-2002071155-A1 | THERMOSETTING ANTI-REFLECTIVE COATINGS COMPRISING ARYL URETHANES OF HYDROXYPROPYL CELLULOSE | BREWER SCIENCE, INC. (US) | 2002-09-12 | — | — | WO | claimed |
| US-20010031428-A1 | Made by reacting a hydroxyalkyl cellulose with an aryl isocyanate such as phenyl isocyanate; coatings have high etch rate and optical density | ARMY, SECRETARY OF THE | 2001-10-18 | — | — | US | claimed |
| US-5229243-A | Addition polymer core, polyurethane or polythiourethane shell | KAO CORPORATION (JP) | 1993-07-20 | — | — | US | claimed |
| US-4578514-A | Synthesis of sulfilimines | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | ALDH1A1 295/4885TDP1 985/4885CYP3A4 433/4885 |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | ATG7, GOT1, ULK1 | ALDH1A1 601/4885TDP1 1533/4885CYP3A4 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.