Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104031 | 0.95 | KDM4E (0.40) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL18101013 | 0.91 | MEN1 (0.40) | TSHRMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL12126281 | 0.86 | ALDH1A1 (0.38) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL751954 | 0.83 | ALDH1A1 (0.54) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL12126258 | 0.83 | MAPT (0.49) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL12261612 | 0.82 | PLA2G2D (0.36) | TSHRTP53TDP1PTPN11HTT | |
| SCHEMBL28186309 | 0.82 | ALDH1A1 (0.59) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL12126278 | 0.82 | CSNK2A1 (0.40) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL12997708 | 0.81 | EGFR (0.42) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL12126271 | 0.81 | KMT2A (0.42) | TSHRTP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8151705-B2 | Method of preparing lithographic printing plate | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100081771-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | US | disclosed |