Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787268 | 0.97 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7975590 | 0.95 | MEN1 (0.31) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28754589 | 0.80 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL19751652 | 0.78 | — | — | |
| SCHEMBL89279 | 0.78 | KMT2A (0.33) | MEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL28162642 | 0.78 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL8945620 | 0.77 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL2484809 | 0.77 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL6047687 | 0.77 | — | — | |
| SCHEMBL9615223 | 0.77 | FDPS (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483959-A | Organic pigments | HERCULES INCORPORATED (US) | 1984-11-20 | — | — | US | disclosed |
| US-4469555-A | OPACIFYING AGENTS FOR PAPER | HERCULES INCORPORATED (US) | 1984-09-04 | — | — | US | disclosed |
| US-4456724-A | GRAFT POLYMERIZING UNSATURATED MONOMER ONTO WATER SOLUBLE CATIONIC PREPOLYMER | HERCULES INCORPORATED (US) | 1984-06-26 | — | — | US | disclosed |
| US-4434267-A | PAPER FILLERS AND COATINGS | HERCULES INCORPORATED (US) | 1984-02-28 | — | — | US | disclosed |
| US-4426483-A | CROSSLINKED GRAFT POLYMERS OF UNSATURATED MONOMERS | HERCULES INCORPORATED (US) | 1984-01-17 | — | — | US | disclosed |
| US-4414353-A | GRAFT POLYMERS AS FILLERS FOR PAPER | HERCULES INCORPORATED (US) | 1983-11-08 | — | — | US | disclosed |
| US-4404310-A | GRAFT POLYMERS OF UNSATURATED COMPOUND ONTO WATER SOLUBLE CATIONIC POLYMERS | HERCULES INCORPORATED (US) | 1983-09-13 | — | — | US | disclosed |
| US-4403062-A | GRAFT POLYMERS OF UNSATURATED COMPOUND ONTO WATER SOLUBLE CATIONIC POLYMERS | HERCULES INCORPORATED (US) | 1983-09-06 | — | — | US | disclosed |
| US-4403063-A | GRAFT POLYMERS, CATIONIC POLYMERS | HERCULES INCORPORATED (US) | 1983-09-06 | — | — | US | disclosed |
| US-4369292-A | LIGHTWEIGHT FILLERS FOR PAPER; PARTICLES FROM FTHE GRAFT COPOLYMERJIZATION OF AN UNSATURATED MONOMER AND A CATIONIC POLYMER | HERCULES INCORPORATED (US) | 1983-01-18 | — | — | US | disclosed |
| US-4235982-A | POLYMERIC FILLERS FOR PAPER | HERCULES, INCORPORATED (US) | 1980-11-25 | — | — | US | disclosed |
| US-4156628-A | TREATMENT WITH CATIONIC AND ANIONIC WATER-SOLUBLE, NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-05-29 | — | — | US | disclosed |
| US-4154646-A | TREATMENT WITH AQUEOUS MIXTURE OF CATIONIC AND ANIONIC WATER-SOLUBLE NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-05-15 | — | — | US | disclosed |
| US-4109053-A | SIZING PAPER WITH STABLE DISPERSIONS OF HYDROCARBON RESINS | HERCULES INCORPORATED (US) | 1978-08-22 | — | — | US | disclosed |
| US-4017431-A | Aqueous dispersions of wax blends and a water-soluble cationic resin and paper sized therewith | HERCULES INCORPORATED (US) | 1977-04-12 | — | — | US | disclosed |
| US-3966684-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966654-A | CATIONIC AMINOPOLYAMIDE-EPICHLOROHYDRIN RESIN | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966694-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3951921-A | PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |
| US-3941736-A | Stable aqueous dispersions of hydrocarbon resins and water soluble polyaminopolyamide-epichlorohydrin resin as dispersing agent | HERCULES INCORPORATED (US) | 1976-03-02 | — | — | US | disclosed |