SCHEMBL89279

SCHEMBL89279

C=CCN(CC(=O)O)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.31
RAB9A P51151 1/20 0.31
EYA2 O00167 1/20 0.30
APP P05067 1/20 0.30
ACE P12821 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1049789 0.82 KMT2A (0.34) KMT2AMEN1ALDH1A1KDM4ERAB9A
Hydrochloric Acid SCHEMBL4943209 0.81 KMT2A (0.33) KMT2AMEN1ALDH1A1KDM4E
SCHEMBL124790 0.80 TDP1 (0.39) KDM4EEYA2APPACETDP1
SCHEMBL787268 0.80 MEN1 (0.32) KMT2AMEN1ALDH1A1
SCHEMBL10615339 0.80 ALDH1A1 (0.32) ALDH1A1RAB9AEYA2APPACE
Hydrochloric Acid SCHEMBL8588133 0.79 MEN1 (0.30) KMT2AMEN1
SCHEMBL17744939 0.79 KMT2A (0.32) KMT2AMEN1ALDH1A1KDM4E
SCHEMBL10888561 0.78 TDP1 (0.38) KDM4EEYA2APPACETDP1
SCHEMBL1470203 0.78 TDP1 (0.38) KDM4EEYA2APPACETDP1
SCHEMBL10894055 0.78 TDP1 (0.38) KDM4EEYA2APPACETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104585228-A MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC 2015-05-06 CN claimed
EP-1853115-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS Monsanto Technology, LLC (US) 2007-11-14 EP claimed
WO-2006096617-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC (US) 2006-09-14 WO claimed
US-20230102424-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC 2023-03-30 US disclosed
US-20200236930-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2020-07-30 US disclosed
EP-1853115-B1 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC (US) 2019-01-09 EP disclosed
US-20170339950-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2017-11-30 US disclosed
CN-104585228-B Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations 孟山都技术公司 2017-05-24 CN disclosed
US-9642359-B2 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2017-05-09 US disclosed
US-20160330956-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2016-11-17 US disclosed
US-9364003-B2 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2016-06-14 US disclosed
CN-104585228-A MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC 2015-05-06 CN disclosed
CN-102792969-B Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC 2015-01-21 CN disclosed
US-20120149569-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2012-06-14 US disclosed
US-8129564-B2 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2012-03-06 US disclosed
EP-1853115-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS Monsanto Technology, LLC (US) 2007-11-14 EP disclosed
US-20070037708-A1 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY, LLC (US) 2007-02-15 US disclosed
WO-2006096617-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC (US) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200236930-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885
US-20070037708-A1 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885
US-20170339950-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885
US-20120149569-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885
US-20230102424-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885
US-20160330956-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR KMT2A 2769/4885MEN1 4751/4885ALDH1A1 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.