Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146272 | 0.88 | PRKCI (0.55) | PRKCIACHECA2CA1PDE10A | |
| SCHEMBL5190794 | 0.84 | PRKCI (0.52) | PRKCIACHECA2CA1PDE10A | |
| SCHEMBL28119969 | 0.83 | RAD52 (0.44) | PRKCIACHECA2CA1PDE10A | |
| SCHEMBL309824 | 0.82 | PRKCI (0.59) | PRKCIACHECA2CA1PDE10A | |
| SCHEMBL29384423 | 0.82 | RAD52 (0.42) | PRKCIACHECA2RAD52MEN1 | |
| SCHEMBL6257247 | 0.82 | RAD52 (0.42) | PRKCIACHECA2RAD52MEN1 | |
| SCHEMBL6157970 | 0.81 | RECQL (0.58) | PRKCIACHECA2CA1PDE10A | |
| SCHEMBL3579492 | 0.81 | PRKCI (0.58) | PRKCIACHEPDE10AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17843137 | 0.80 | RAD52 (0.45) | PRKCIACHECA2RAD52MEN1 | |
| Hydrochloric Acid SCHEMBL22283009 | 0.80 | RAD52 (0.45) | PRKCIACHECA2RAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093365-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-1984000032-A1 | AMINO-OXY-(MERCAPTO-ALKYL)-BENZENES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL PRODUCTS CONTAINING THEM | SANDOZ AG (CH) | 1984-01-05 | — | — | WO | disclosed |