SCHEMBL6157970

SCHEMBL6157970

NCCc1cc(N)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 4/20 0.58
TDP1 Q9NUW8 4/20 0.58
MEN1 O00255 2/20 0.58
RAD52 P43351 2/20 0.58
KMT2A Q03164 2/20 0.58
APEX1 P27695 2/20 0.58
BLM P54132 2/20 0.58
GAPDH P04406 1/20 0.58
THRB P10828 1/20 0.58
PRKCI P41743 1/20 0.57
KDM4E B2RXH2 3/20 0.56
MAPT P10636 3/20 0.56
MAPK1 P28482 3/20 0.56
TAAR1 Q96RJ0 2/20 0.56
ALOX15 P16050 2/20 0.56
HSD17B10 Q99714 2/20 0.56
AGO2 Q9UKV8 1/20 0.56
ACHE P22303 3/20 0.55
BACE1 P56817 1/20 0.50
ADRA2A P08913 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4820909 0.98 RECQL (0.59) RECQLTDP1MEN1RAD52KMT2A
Hydrochloric Acid SCHEMBL29355907 0.98 RECQL (0.59) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL5190794 0.90 PRKCI (0.52) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL22117739 0.87 PRKCI (0.53) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL146272 0.84 PRKCI (0.55) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL34055 0.84 PRKCI (0.59) RECQLTDP1MEN1KMT2AAPEX1
SCHEMBL5381058 0.83 PRKCI (0.63) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL23412633 0.82 RECQL (0.58) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL1044776 0.82 RECQL (0.58) RECQLTDP1MEN1RAD52KMT2A
Hydrochloric Acid SCHEMBL1986970 0.82 ACHE (0.60) RECQLTDP1MEN1RAD52KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1200682-C Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2005-05-11 CN claimed
CN-1286618-A Keratinous fibre oxidation dyeing composition contg. laccase and dyeing method using same OREAL (FR) 2001-03-07 CN claimed
CN-1286619-A Keratinous fibre oxidationdyeing composition contg. laccase and dyeing method using same OREAL (FR) 2001-03-07 CN claimed
CN-1278427-A Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2001-01-03 CN claimed
CN-1096797-A They carry out painted method dyeing composition for keratinous fibres and application OREAL (FR) 1994-12-28 CN claimed
CN-100534411-C Oxidation dyeing method using N-acetyl cysteine as reducing agent and laccase as oxidizing agent OREAL (FR) 2009-09-02 CN disclosed
CN-1250196-C Oxidizing composition and use thereof for dyeing, permanent shaping or bleaching keratin fibres OREAL (FR) 2006-04-12 CN disclosed
CN-1203835-C Dye composition comprising laccase and process for dyeing keratinous fibres OREAL (FR) 2005-06-01 CN disclosed
CN-1200682-C Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2005-05-11 CN disclosed
CN-1195482-C Composition for the oxidation dyeing of keratinous fibres comprising a laccase and dyeing process using this composition OREAL (FR) 2005-04-06 CN disclosed
EP-1301163-B1 OXIDATIVE HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2,4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT HENKEL KGAA (DE) 2005-01-26 EP disclosed
EP-1301163-A1 OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-16 EP disclosed
CN-1241134-A Oxidising composition and uses for dyeing, permanently setting or bleaching keratin fibres OREAL (FR) 2000-01-12 CN disclosed
CN-1239422-A Oxidation dyeing compsn. for keratin fibres and dyeing method of using same OREAL (FR) 1999-12-22 CN disclosed
US-5866619-A SACCHARIDE-CONTAINING POLYMER MATRIX PERIO PRODUCTS LTD. (IL) 1999-02-02 US disclosed
US-5525634-A A MATRIX COMPRISING A SACCHARIDE-CONTAINING POLYMER THAT IS RESISTANT TO CHEMICAL AND ENZYMATIC DEGRADATION IN THE STOMACH AND SMALL INTESTINE PERIO PRODUCTS, LTD. (IL) 1996-06-11 US disclosed
CN-1096797-A They carry out painted method dyeing composition for keratinous fibres and application OREAL (FR) 1994-12-28 CN disclosed
EP-0527942-A4 COLONIC DRUG DELIVERY SYSTEM PERIO PROD LTD (IL) 1993-10-13 EP disclosed
EP-0527942-A1 COLONIC DRUG DELIVERY SYSTEM Perio Products Limited (IL) 1993-02-24 EP disclosed
WO-1991016881-A1 COLONIC DRUG DELIVERY SYSTEM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) 1991-11-14 WO disclosed