SCHEMBL146272

SCHEMBL146272

Nc1ccc(O)c(CCO)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.55
ACHE P22303 3/20 0.53
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
PDE10A Q9Y233 1/20 0.45
KDM4E B2RXH2 5/20 0.43
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
BACE1 P56817 2/20 0.43
GAA P10253 2/20 0.43
ALOX5 P09917 1/20 0.43
RECQL P46063 5/20 0.41
TDP1 Q9NUW8 5/20 0.41
ALOX15 P16050 4/20 0.41
HSD17B10 Q99714 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
THRB P10828 2/20 0.41
CASP1 P29466 2/20 0.41
HIF1A Q16665 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042437 0.88 PRKCI (0.52) PRKCIACHECA1CA2PDE10A
SCHEMBL6157970 0.84 RECQL (0.58) PRKCIACHECA1CA2PDE10A
Hydrochloric Acid SCHEMBL29355907 0.83 RECQL (0.59) PRKCIACHECA1CA2PDE10A
SCHEMBL6152292 0.83 TYR (0.46) PRKCIACHECA1CA2PDE10A
Hydrochloric Acid SCHEMBL4820909 0.83 RECQL (0.59) PRKCIACHECA1CA2PDE10A
SCHEMBL33926 0.82 PRKCI (0.59) PRKCIACHECA1CA2PDE10A
SCHEMBL4625444 0.81 PRKCI (0.46) PRKCIACHECA1CA2PDE10A
SCHEMBL6141822 0.81 PRKCI (0.42) PRKCIACHECA1CA2PDE10A
SCHEMBL22117739 0.81 PRKCI (0.53) PRKCIACHECA1CA2PDE10A
SCHEMBL5381058 0.81 PRKCI (0.63) PRKCIACHECA1CA2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1074 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803438-B1 Developer-coupler combination HENKEL AG & CO KGAA (DE) 2015-09-02 EP claimed
EP-1494995-B1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS PROCTER & GAMBLE (US) 2010-09-22 EP claimed
EP-1752192-B1 Oxidizing hair coloring agents containing m-Aminophenol derivatives PROCTER & GAMBLE (US) 2010-02-03 EP claimed
CN-100549003-C 3-aminophenol derivatives and keratin fibre colorants comprising these compounds P & G CLAIROL INC (US) 2009-10-14 CN claimed
US-7491244-B2 Oxidizing hair coloring agents containing m-aminophenol derivatives THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US claimed
EP-1670423-B1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-10-08 EP claimed
CN-100358887-C m-aminophenol derivatives and dyes containing these compounds P & G CLAIROL INC (US) 2008-01-02 CN claimed
CN-100349886-C 1, 3-dihydroxybenzene derivatives and coloring agents containing the same WELLA AG (US) 2007-11-21 CN claimed
CN-100346768-C Oxidation hair dye agent comprising 3-aminophenol derivative and novel 3-aminophenol derivative P & G CLAIROL INC (US) 2007-11-07 CN claimed
EP-1846361-A2 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 2007-10-24 EP claimed
EP-0370880-A1 Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair L'OREAL (FR) 1990-05-30 EP claimed
US-4891045-A DYEING HAIR L'OREAL (FR) 1990-01-02 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986002829-A1 OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-22 WO claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed