SCHEMBL11042745

SCHEMBL11042745

COc1cc(-c2ccc(N)c(OC)c2)ccc1N.COc1ccc(N)cc1.COc1ccc(N)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.74
CYP3A4 P08684 3/20 0.74
TDP1 Q9NUW8 3/20 0.74
HSD17B10 Q99714 3/20 0.74
TSHR P16473 1/20 0.74
MAPK1 P28482 2/20 0.59
APP P05067 2/20 0.53
MAPT P10636 3/20 0.50
CHEK1 O14757 3/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
TP53 P04637 1/20 0.50
NFKB1 P19838 1/20 0.50
RAB9A P51151 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649720 0.90 ALDH1A1 (0.83) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL29399235 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL48945 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Methane SCHEMBL28975440 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL622811 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL30913021 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL30053031 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Ammonia Solution, Strong SCHEMBL2259240 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL29494721 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL3947578 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60031566-A None JP disclosed
JP-S6031566-A DISAZO COMPOUND AND DYEING THEREWITH NIPPON KAYAKU CO LTD 1985-02-18 JP disclosed