SCHEMBL649720

SCHEMBL649720

COc1cc(-c2ccc(N)cc2)ccc1N

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.83
TDP1 Q9NUW8 4/20 0.83
CYP3A4 P08684 3/20 0.83
HSD17B10 Q99714 2/20 0.83
TSHR P16473 1/20 0.83
MAPK1 P28482 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CHEK1 O14757 5/20 0.51
FYN P06241 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
TP53 P04637 1/20 0.46
APP P05067 1/20 0.46
ADRA2B P18089 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48945 0.91 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4HSD17B10TSHR
SCHEMBL29399235 0.91 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4HSD17B10TSHR
SCHEMBL11042745 0.90 ALDH1A1 (0.74) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Hydrochloric Acid SCHEMBL29494721 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Hydrochloric Acid SCHEMBL30053031 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Hydrochloric Acid SCHEMBL622811 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Ammonia Solution, Strong SCHEMBL2259240 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Hydrochloric Acid SCHEMBL30913021 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Methane SCHEMBL28975440 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR
Hydrochloric Acid SCHEMBL3947578 0.89 ALDH1A1 (0.95) ALDH1A1TDP1CYP3A4HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
CN-118871548-A Photoalignment materials 罗利克技术有限公司 2024-10-29 CN disclosed
CN-116355434-B Method for preparing direct dye by replacing benzidine 广东省科学院测试分析研究所(中国广州分析测试中心) 2024-07-09 CN disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
US-11957695-B2 Methods and compositions targeting glucocorticoid signaling for modulating immune responses THE BROAD INSTITUTE, INC. (US) 2024-04-16 US disclosed
US-20060042750-A1 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-03-02 US disclosed
US-20050214552-A1 Flexible metal foil-polyimide laminate and making method SHIN-ETSU CHEMICAL CO., LTD. 2005-09-29 US disclosed
US-20050121138-A1 Preparation of flexible metal foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. 2005-06-09 US disclosed
US-20040265601-A1 Polyimide precursor resin solution composition sheet SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-30 US disclosed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US disclosed
EP-0428020-A2 Blends of polyarylene sulfides, nitrogroup containing crosslinkers and glassfibres BAYER AG (DE) 1991-05-22 EP disclosed
EP-0315216-A2 Polyimides, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 ALDH1A1 1606/4885TDP1 2088/4885CYP3A4 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.