SCHEMBL11042835

SCHEMBL11042835

CCOC(=O)c1cccc(N(C(=O)O)c2ccccc2N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.49
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
MAPT P10636 4/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PRMT1 Q99873 1/20 0.43
SENP1 Q9P0U3 1/20 0.43
ESRRA P11474 1/20 0.43
MEP1B Q16820 1/20 0.43
LMNA P02545 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4926537 0.79 CYP4F2 (0.52) CDC25BALDH1A1CYP4F2CYP4A11MAPT
SCHEMBL10106410 0.78 PTPN1 (0.58) ALDH1A1CYP4F2CYP4A11MAPTMEN1
SCHEMBL6445553 0.77 MAPT (0.53) CDC25BALDH1A1CYP4F2CYP4A11MAPT
SCHEMBL10106412 0.77 KMT2A (0.52) ALDH1A1CYP4F2CYP4A11MAPTMEN1
SCHEMBL11001769 0.76 ALDH1A1 (0.47) CDC25BALDH1A1HSD17B10MAPTKDM4E
SCHEMBL11041208 0.76 ALDH1A1 (0.52) CDC25BALDH1A1HSD17B10MAPTKDM4E
SCHEMBL10145056 0.75 CYP4F2 (0.50) ALDH1A1HSD17B10CYP4F2CYP4A11MAPT
SCHEMBL3236449 0.74 MAPT (0.65) ALDH1A1HSD17B10CYP4F2CYP4A11MAPT
SCHEMBL32685467 0.74 MAPT (0.65) ALDH1A1HSD17B10CYP4F2CYP4A11MAPT
SCHEMBL10145069 0.74 CYP4F2 (0.52) ALDH1A1CYP4F2CYP4A11MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-87100159-A The application of film regulatory factor and contain the product of this film regulatory factor 1987-09-16 CN disclosed
EP-0102003-A1 Stabilised herbicide composition based on meta-biscarbamates S.I.P.C.A.M. S.p.A. Società Italiana Prodotti Chimici e per l'Agricoltura Milano (IT) 1984-03-07 EP disclosed
US-4323469-A SACCHARIN DERIVATIVE IN ADMIXTURE WITH A BASE AND A SOLVENT CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1982-04-06 US disclosed
US-4315861-A Process for O-acylating phenol derivatives and acylating compositions for this purpose Chinoin Gyogyszer RT (HU) 1982-02-16 US disclosed