SCHEMBL11041208

SCHEMBL11041208

CCOC(=O)c1cccc(N(C(=O)O)c2ccccc2)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 2/20 0.51
CDC25B P30305 4/20 0.46
HPGD P15428 4/20 0.46
MAPT P10636 4/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALOX15 P16050 2/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
NPC1 O15118 2/20 0.41
TP53 P04637 1/20 0.41
MAPK10 P53779 2/20 0.41
POLB P06746 1/20 0.41
CDC25A P30304 1/20 0.40
CDC25C P30307 1/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27424975 0.78 TSHR (0.70) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL10545481 0.77 RAB9A (0.41) ALDH1A1HSD17B10HPGDMAPTRAB9A
SCHEMBL28845709 0.76 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL11042835 0.76 CDC25B (0.49) ALDH1A1HSD17B10CDC25BHPGDMAPT
SCHEMBL27894063 0.76 TSHR (0.54) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL31091521 0.75 CA12 (0.62) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL983755 0.75 CA12 (0.62) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL13816768 0.75 ALDH1A1 (0.62) ALDH1A1HSD17B10TSHRCDC25BHPGD
SCHEMBL27946424 0.75 TSHR (0.61) ALDH1A1HSD17B10TSHRCDC25BSMN1; SMN2
SCHEMBL21072076 0.74 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCDC25BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0102003-A1 Stabilised herbicide composition based on meta-biscarbamates S.I.P.C.A.M. S.p.A. Società Italiana Prodotti Chimici e per l'Agricoltura Milano (IT) 1984-03-07 EP claimed
EP-0102003-A1 Stabilised herbicide composition based on meta-biscarbamates S.I.P.C.A.M. S.p.A. Società Italiana Prodotti Chimici e per l'Agricoltura Milano (IT) 1984-03-07 EP disclosed
US-4323469-A SACCHARIN DERIVATIVE IN ADMIXTURE WITH A BASE AND A SOLVENT CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1982-04-06 US disclosed
US-4315861-A Process for O-acylating phenol derivatives and acylating compositions for this purpose Chinoin Gyogyszer RT (HU) 1982-02-16 US disclosed