Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763406 | 0.89 | ALDH1A1 (0.41) | TSHRCYP1A2ALDH1A1TDP1MITF | |
| SCHEMBL372982 | 0.84 | TSHR (0.46) | TSHRHSD17B10CYP1A2CYP2D6NFKB1 | |
| SCHEMBL997695 | 0.82 | TSHR (0.46) | TSHRHSD17B10CYP1A2CYP2D6NFKB1 | |
| SCHEMBL1487355 | 0.81 | TSHR (0.42) | TSHRHSD17B10CYP1A2CYP2D6NFKB1 | |
| SCHEMBL8978744 | 0.78 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1MITF | |
| SCHEMBL78218 | 0.77 | ALDH1A1 (0.41) | TSHRCYP2D6ALDH1A1HTR1AADRA2A | |
| SCHEMBL29377653 | 0.77 | ALDH1A1 (0.48) | TSHRCYP1A2LMNABLMMAPT | |
| SCHEMBL595200 | 0.77 | ALDH1A1 (0.48) | TSHRCYP1A2LMNABLMMAPT | |
| SCHEMBL7027241 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1MITF | |
| SCHEMBL14732598 | 0.76 | TSHR (0.49) | TSHRHSD17B10CYP1A2CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471079-A | POLYMERIC DYE FROM POLYMER CONTAINING AMINO GROUPS AND ANIONIC OR REACTIVE DYE | PILOT MAN-NEN HITSU KABUSHIKI KAISHA (JP) | 1984-09-11 | — | — | US | disclosed |