SCHEMBL7763406

SCHEMBL7763406

C=Cc1ccccc1CCBr

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.39
MITF O75030 1/20 0.33
TSHR P16473 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042852 0.89 TSHR (0.41) ALDH1A1TDP1MITFTSHRCYP1A2
SCHEMBL8978744 0.88 ALDH1A1 (0.39) ALDH1A1TDP1MITFTSHR
SCHEMBL29377653 0.86 ALDH1A1 (0.48) ALDH1A1TDP1MITFTSHRCYP1A1
SCHEMBL595200 0.86 ALDH1A1 (0.48) ALDH1A1TDP1MITFTSHRCYP1A1
SCHEMBL7027241 0.86 ALDH1A1 (0.38) ALDH1A1TDP1MITF
SCHEMBL7026110 0.84 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL7031317 0.84 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL5072509 0.84 ALDH1A1 (0.46) ALDH1A1TDP1MITFTSHRCYP1A1
SCHEMBL183723 0.82 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCYP1A1CYP1A2
SCHEMBL6278153 0.82 ALDH1A1 (0.44) ALDH1A1TDP1MITFTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
CN-104045663-A Symmetric hyperbranched silicone-modified polymerizable compound and modularized manufacturing method thereof SHINETSU CHEMICAL CO 2014-09-17 CN disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
EP-0670184-B1 Method of demineralizing water or an aqueous solution MITSUBISHI CHEM CORP (JP) 2001-09-05 EP disclosed
US-5518627-A DEMINERALIZATION, BASIC ANION EXCHANGE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 1996-05-21 US disclosed
EP-0670184-A2 Method of demineralizing water or an aqueous solution Mitsubishi Chemical Corporation (JP) 1995-09-06 EP disclosed