SCHEMBL11042877

SCHEMBL11042877

Nc1ccc(OCC2CC2(Cl)Cl)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.38
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HPGD P15428 3/20 0.33
PDE7A Q13946 1/20 0.33
DRD4 P21917 1/20 0.33
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SYK P43405 1/20 0.33
CSNK2A1 P68400 1/20 0.33
POLB P06746 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30781076 0.79 KMO (0.47) CYP3A4TSHRALDH1A1HTTHPGD
SCHEMBL2562599 0.79 KMO (0.47) CYP3A4TSHRALDH1A1HTTHPGD
SCHEMBL11321952 0.77 ALDH1A1 (0.38) MRGPRX4CYP3A4TSHRALDH1A1HTT
SCHEMBL30882116 0.76 HPGD (0.50) HPGD
SCHEMBL22069677 0.76 HPGD (0.50) HPGDCSNK2A1
SCHEMBL23328015 0.76 HPGD (0.50) HPGD
SCHEMBL11042610 0.76 MAPT (0.50) CYP3A4ALDH1A1HPGDPDE7ASMN1; SMN2
SCHEMBL30140430 0.75 HTR2C (0.37) MRGPRX4CYP3A4TSHRALDH1A1HTT
SCHEMBL11044021 0.75 TDP1 (0.46) MRGPRX4CYP3A4TSHRHPGD
SCHEMBL10188109 0.74 DRD4 (0.46) CYP3A4ALDH1A1HTTHPGDDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479822-A POSTEMERGENCE HERBICIDE SCHERING AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed