Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | Q9HBH1 | 1/20 | 0.44 | |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883776 | 1.00 | CA1 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL11128090 | 1.00 | CA1 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL8232200 | 0.94 | ZDHHC7 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL19085541 | 0.94 | ZDHHC7 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL17378386 | 0.90 | GNPAT (0.42) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL8234349 | 0.90 | TRPV1 (0.43) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL3241409 | 0.88 | TAS1R3 (0.46) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL711890 | 0.88 | TAS1R3 (0.46) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL23133171 | 0.86 | BIRC2 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 | |
| SCHEMBL21485282 | 0.86 | BIRC2 (0.53) | CA1CA2TAS1R3TAS1R1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484414-B | Process for preparing optically active 3-aminocarboxylic acid esters | BASF SE | 2012-11-21 | — | — | CN | disclosed |
| WO-2011146974-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| EP-0076917-B1 | PROCESS FOR MAKING N-ACETYL-2,3-DEHYDROAMINOCARBOXYLIC-ACID ESTERS | Degussa Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | disclosed |
| US-4456766-A | Process for the production of N-acetyl-2,3-dehydro-aminocarboxylic acid esters | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | disclosed |
| EP-0076917-A2 | Process for making N-acetyl-2,3-dehydroaminocarboxylic-acid esters | Degussa Aktiengesellschaft (DE) | 1983-04-20 | — | — | EP | disclosed |