Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232200 | 1.00 | ZDHHC7 (0.53) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL27883776 | 0.94 | CA1 (0.53) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL11042902 | 0.94 | CA1 (0.53) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL11128090 | 0.94 | CA1 (0.53) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL8234349 | 0.92 | TRPV1 (0.43) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL17378386 | 0.88 | GNPAT (0.42) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL12038919 | 0.87 | ZDHHC7 (0.49) | ZDHHC7SIRT1SIRT6PLA2G2ABIRC2 | |
| SCHEMBL3241409 | 0.86 | TAS1R3 (0.46) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL711890 | 0.86 | TAS1R3 (0.46) | ZDHHC7SIRT1SIRT6CA1CA2 | |
| SCHEMBL14944700 | 0.86 | CA1 (0.41) | ZDHHC7SIRT1SIRT6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289951-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2018081480-A1 | LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2018-05-03 | — | — | WO | disclosed |
| WO-2017117528-A1 | LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics, Inc. (CA) | 2017-07-06 | — | — | WO | disclosed |