Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041928 | 0.82 | KMT2A (0.71) | KMT2APDK2MMP9MMP8MEN1 | |
| SCHEMBL74450 | 0.77 | KMT2A (0.53) | KMT2APDK2ALDH1A1MAPTMEN1 | |
| SCHEMBL2494879 | 0.77 | KMT2A (0.53) | KMT2AMAPTMEN1GAA | |
| SCHEMBL15974346 | 0.77 | ALDH1A1 (0.44) | KMT2AL3MBTL1GLAALDH1A1MAPT | |
| SCHEMBL1464852 | 0.76 | KMT2A (0.59) | KMT2AALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL5674361 | 0.76 | KMT2A (0.48) | KMT2APDK2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1588395 | 0.75 | KMT2A (0.47) | KMT2APDK2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL75146 | 0.75 | KMT2A (0.50) | KMT2APDK2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL5276123 | 0.74 | KMT2A (0.68) | KMT2APDK2ALDH1A1MAPTNPSR1 | |
| SCHEMBL11040903 | 0.73 | KMT2A (0.47) | KMT2APDK2MMP9MMP8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454320-A | Process for 5-substituted dialuric acids | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |