SCHEMBL11042964

SCHEMBL11042964

C=CCC(C=C)(CCCC)C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.33
FAAH O00519 1/20 0.33
HPGD P15428 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042472 0.89
SCHEMBL7059895 0.83 CES2 (0.40) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL15859490 0.81 CES2 (0.41) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL5961394 0.81 CES2 (0.41) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL4662016 0.81 CES2 (0.41) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL11043110 0.80 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL11040959 0.80 TSHR (0.32) TSHRHPGDZDHHC20ZDHHC2
SCHEMBL9324160 0.78 CES2 (0.39) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL5280547 0.78 CES2 (0.39) TSHRFAAHZDHHC20ZDHHC2
SCHEMBL11043798 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed