Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145146 | 0.80 | ACP3 (0.43) | ACP3ALDH1A1CES2CES1HIF1A | |
| SCHEMBL3113218 | 0.80 | ACP3 (0.43) | ACP3ALDH1A1CES2CES1HIF1A | |
| SCHEMBL9297918 | 0.78 | ACP3 (0.42) | ACP3ALDH1A1CES2CES1HIF1A | |
| SCHEMBL29107358 | 0.78 | CXCL8 (0.46) | ACP3ALDH1A1CES2CES1ADRB2 | |
| SCHEMBL9297917 | 0.78 | ACP3 (0.42) | ACP3ALDH1A1CES2CES1HIF1A | |
| SCHEMBL485065 | 0.77 | ACP3 (0.53) | ACP3ALDH1A1HIF1AADRB2ADRB1 | |
| SCHEMBL6205203 | 0.77 | CES2 (0.43) | ACP3ALDH1A1CES2CES1HIF1A | |
| SCHEMBL7589814 | 0.77 | TDP1 (0.55) | ACP3ALDH1A1CES2CES1TSHR | |
| SCHEMBL7724344 | 0.76 | CES2 (0.48) | ALDH1A1CES2CES1HIF1A | |
| SCHEMBL7723973 | 0.76 | ESR1 (0.45) | ACP3ALDH1A1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |