SCHEMBL11043349

SCHEMBL11043349

C[SiH](C)C=CCn1cncn1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.36
CYP19A1 P11511 5/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSP90AA1 P07900 1/20 0.31
UGT1A4 P22310 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14207967 0.78
SCHEMBL11014159 0.74 MAPT (0.45) CYP19A1ALDH1A1MAPTSMN1; SMN2HSP90AA1
SCHEMBL13374031 0.73 FDPS (0.36) FDPSCYP19A1EGLN3ALDH1A1MAPT
SCHEMBL11013990 0.71 CYP19A1 (0.44) CYP19A1SMN1; SMN2HSP90AA1
SCHEMBL4433009 0.69
SCHEMBL9427892 0.69
SCHEMBL9729237 0.66 CYP19A1 (0.51) CYP19A1MAPTHSP90AA1
SCHEMBL10697241 0.64
SCHEMBL5657617 0.64 CYP19A1 (0.48) FDPSCYP19A1EGLN3ALDH1A1MAPT
SCHEMBL10505307 0.61 CYP19A1 (0.42) FDPSCYP19A1EGLN3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148026-A2 Fungicidal imidazoles and triazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-10 EP disclosed