Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043349 | 0.74 | FDPS (0.36) | MAPTCYP19A1SMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL11013990 | 0.70 | CYP19A1 (0.44) | LMNAKMT2ACYP19A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL9729237 | 0.70 | CYP19A1 (0.51) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL11243013 | 0.70 | CYP19A1 (0.51) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL7674570 | 0.68 | CYP19A1 (0.79) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL11016712 | 0.67 | CYP19A1 (0.51) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL10947085 | 0.67 | CYP19A1 (0.50) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL10940175 | 0.67 | CYP19A1 (0.50) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL6442620 | 0.66 | CYP19A1 (0.55) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL11031755 | 0.66 | MAPT (0.49) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148026-A2 | Fungicidal imidazoles and triazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |