Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL11043394

C=CC(=O)O.C=CC(=O)OCC.C=COC(C)=O

nearest known ligand 0.46

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.46
TSHR P16473 7/20 0.43
HPGD P15428 1/20 0.43
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 2/20 0.40
LMNA P02545 2/20 0.40
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
THRB P10828 2/20 0.37
NPSR1 Q6W5P4 1/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GLO1 Q04760 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL8060405 0.94 TSHR (0.47) HCAR2TSHRHPGDALDH1A1HSD17B10
Maleic Acid SCHEMBL1766045 0.93 HCAR2 (0.56) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL28542637 0.91 TSHR (0.44) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL6260803 0.90 TSHR (0.41) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL28020506 0.87 HCAR2 (0.58) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL40332 0.87 HCAR2 (0.58) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL8587658 0.87 HCAR2 (0.58) HCAR2TSHRHPGDALDH1A1HSD17B10
Acrylic Acid Ethyl Ester SCHEMBL7633351 0.85 HCAR2 (0.56) HCAR2TSHRHPGDALDH1A1HSD17B10
Ethyl Fumarate SCHEMBL9678685 0.84 HCAR2 (0.69) HCAR2ALDH1A1HSD17B10LMNANPSR1
Urethane SCHEMBL9436175 0.84 ALOX15 (0.52) HCAR2TSHRHPGDALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0015627-B1 MODIFIED MONOOLEFIN COPOLYMER ELASTOMER WITH IMPROVED HEAT AND OIL RESISTANCE UNIROYAL, INC. (US) 1984-08-08 EP disclosed
US-4316971-A ETHYLENE, ACRYLIC ESTER, COPOLYENES UNIROYAL, INC. (US) 1982-02-23 US disclosed
EP-0015627-A1 Modified monoolefin copolymer elastomer with improved heat and oil resistance UNIROYAL, INC. (US) 1980-09-17 EP disclosed