SCHEMBL11043540

SCHEMBL11043540

CCCC(CCC)CC(C)C(C)O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
METAP1 P53582 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1658348 0.79 TSHR (0.48) TSHRMETAP1LMNA
SCHEMBL10927344 0.77
SCHEMBL425153 0.77
SCHEMBL15188474 0.77
SCHEMBL320967 0.75 CA2 (0.36) TSHRMETAP1LMNA
SCHEMBL4269752 0.73 CA12 (0.36) TSHRLMNA
SCHEMBL8897441 0.72 TSHR (0.33) TSHRLMNA
SCHEMBL11526148 0.71 TSHR (0.36) TSHR
SCHEMBL4951456 0.70 SLC1A3 (0.37) TSHRMETAP1LMNA
SCHEMBL1657134 0.70 ACE2 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed