SCHEMBL8897441

SCHEMBL8897441

CCCC(O)CC(CCC)CCC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
FDPS P14324 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637129 0.95 LMNA (0.31) TSHRLMNA
SCHEMBL20298367 0.89 ALDH1A1 (0.37) TSHRLMNATDP1CYP3A4CA2
SCHEMBL9720248 0.87 LMNA (0.41) TSHRLMNATDP1CYP3A4
SCHEMBL15178124 0.86 ALDH1A1 (0.39) TSHRLMNACHRM1AKR1A1CHRM3
SCHEMBL15178058 0.86 ALDH1A1 (0.39) TSHRLMNACHRM1AKR1A1CHRM3
SCHEMBL16074695 0.86 LMNA (0.44) TSHRLMNACHRM1AKR1A1CHRM3
SCHEMBL28316988 0.85 TSHR (0.33) TSHRADRA1A
SCHEMBL16153750 0.84 TSHR (0.38) TSHRLMNACHRM1AKR1A1CHRM3
SCHEMBL28576046 0.84 TSHR (0.38) TSHRLMNACHRM1AKR1A1CHRM3
SCHEMBL3096192 0.84 TSHR (0.38) TSHRLMNACHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed