SCHEMBL11043552

SCHEMBL11043552

C=CCC(C)(C)C=C(CCCC)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.38
TSHR P16473 2/20 0.33
CES2 O00748 1/20 0.33
FAAH O00519 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA1 P00915 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043551 1.00 CES1 (0.38) CES1TSHRCES2FAAHALDH1A1
SCHEMBL3151539 0.73 CES1 (0.43) CES1TSHRCES2FAAHALDH1A1
SCHEMBL3151546 0.73 CES1 (0.43) CES1TSHRCES2FAAHALDH1A1
SCHEMBL11040823 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11040824 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11044546 0.71
SCHEMBL11044551 0.71
SCHEMBL11043130 0.70 CES1 (0.42) CES1TSHRCES2FAAHALDH1A1
SCHEMBL11043125 0.70 CES1 (0.42) CES1TSHRCES2FAAHALDH1A1
SCHEMBL3768339 0.69 FAAH (0.41) CES1TSHRCES2FAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed