SCHEMBL11043879

SCHEMBL11043879

c1ccc(NC(Nc2ccccc2)(Nc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.46
ALDH1A1 P00352 7/20 0.43
TDP1 Q9NUW8 4/20 0.43
HSD17B10 Q99714 3/20 0.43
CTSD P07339 1/20 0.43
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
AR P10275 1/20 0.42
TSHR P16473 5/20 0.41
PTGS2 P35354 2/20 0.41
MAPK1 P28482 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2B P41595 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
IDO1 P14902 2/20 0.39
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279906 0.78 KCNN4 (0.52) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL6929062 0.78 ALDH1A1 (0.43) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL4801311 0.74 KCNN4 (0.48) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL3225192 0.74 TSHR (0.48) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL10785149 0.74 KCNN4 (0.48) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL10876233 0.74 ALDH1A1 (0.48) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL450601 0.74 MAPKAPK2 (0.46) KCNN4ALDH1A1TDP1HSD17B10CTSD
Hydrochloric Acid SCHEMBL8507149 0.72 MAPKAPK2 (0.45) KCNN4ALDH1A1TDP1HSD17B10CTSD
SCHEMBL28606716 0.71 ALDH1A1 (0.47) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL7672445 0.70 TAAR1 (0.41) KCNN4ALDH1A1HSD17B10MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024898-B1 SOLVENTS, SOLUTIONS, AND PRESSURE-SENSITIVE MARK-RECORDING SYSTEMS MONSANTO EUROPE S.A./N.V. (BE) 1984-06-27 EP disclosed
US-4335013-A COMPRISING A BLEND OF AN AROMATIC HYDROCARBON AND A DIESTER MONSANTO COMPANY (US) 1982-06-15 US disclosed