SCHEMBL6929062

SCHEMBL6929062

c1ccc(NC(Nc2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
TDP1 Q9NUW8 4/20 0.43
HSD17B10 Q99714 3/20 0.43
CTSD P07339 1/20 0.43
TSHR P16473 5/20 0.41
PTGS2 P35354 2/20 0.41
MAPK1 P28482 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2B P41595 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KCNN4 O15554 4/20 0.40
IDO1 P14902 2/20 0.39
CYP3A4 P08684 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877109 0.84 MAPT (0.52) ALDH1A1TDP1HSD17B10TSHRMAPK1
SCHEMBL28877110 0.79 ALDH1A1 (0.57) ALDH1A1TDP1HSD17B10TSHRMAPK1
SCHEMBL11043879 0.78 KCNN4 (0.46) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL11279906 0.78 KCNN4 (0.52) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL2268564 0.74 POLB (0.42) ALDH1A1TDP1TSHRPTGS2ALOX12
SCHEMBL4801311 0.74 KCNN4 (0.48) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL3225192 0.74 TSHR (0.48) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL10876233 0.74 ALDH1A1 (0.48) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL10785149 0.74 KCNN4 (0.48) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL450601 0.74 MAPKAPK2 (0.46) ALDH1A1TDP1HSD17B10CTSDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
EP-1023377-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-08-02 EP claimed
EP-0694057-B1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEM CO INC (US) 2000-03-01 EP claimed
WO-1999016821-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-12145898-B2 Compound, composition comprising same, and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2024-11-19 US disclosed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
WO-1996012760-A2 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-05-02 WO disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12145898-B2 Compound, composition comprising same, and organic light emitting diode comprising same CRY1, SEM1, NOTUM ALDH1A1 9/4885TDP1 1698/4885HSD17B10 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.