Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043916 | 1.00 | CES1 (0.42) | CES1CES2RAB9ANPC1GAA | |
| SCHEMBL11041292 | 0.82 | CA2 (0.39) | CES1CES2RAB9ANPC1GAA | |
| SCHEMBL11041287 | 0.82 | CA2 (0.39) | CES1CES2RAB9ANPC1GAA | |
| SCHEMBL20919883 | 0.79 | CES1 (0.48) | CES1CES2ALDH1A1PTGS1MLYCD | |
| SCHEMBL28269583 | 0.79 | CES1 (0.48) | CES1CES2ALDH1A1PTGS1MLYCD | |
| SCHEMBL4412147 | 0.78 | CES1 (0.48) | CES1CES2RAB9ANPC1HSD17B10 | |
| SCHEMBL29117952 | 0.78 | CES1 (0.43) | CES1CES2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3731523 | 0.74 | CES1 (0.48) | CES1CES2RAB9ANPC1ALDH1A1 | |
| SCHEMBL15137342 | 0.72 | CES1 (0.46) | CES1CES2RAB9ANPC1ALDH1A1 | |
| SCHEMBL15137388 | 0.72 | CES1 (0.46) | CES1CES2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485252-A | INSECTICIDES AND MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-27 | — | — | US | disclosed |
| EP-0019787-B1 | 2-PHENYLALKEN-1-YL-CYCLOPROPANE-CARBOXYLIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES AND ACARICIDES; INTERMEDIATES IN THEIR PREPARATION | BAYER AG (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4344963-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0019787-A2 | 2-Phenylalken-1-yl-cyclopropane-carboxylic acid esters, process for their preparation and their use as insecticides and acaricides; intermediates in their preparation | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |