Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041292 | 1.00 | CA2 (0.39) | CA2MAPTALDH1A1HTTNPSR1 | |
| SCHEMBL11043913 | 0.82 | CES1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ACES2 | |
| SCHEMBL11043916 | 0.82 | CES1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ACES2 | |
| SCHEMBL18827517 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11041996 | 0.72 | MEN1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL11041994 | 0.72 | MEN1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL11433697 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL15182823 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11499357 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL19445934 | 0.68 | ALDH1A1 (0.35) | CA2MAPTALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485252-A | INSECTICIDES AND MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-27 | — | — | US | disclosed |
| EP-0019787-B1 | 2-PHENYLALKEN-1-YL-CYCLOPROPANE-CARBOXYLIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES AND ACARICIDES; INTERMEDIATES IN THEIR PREPARATION | BAYER AG (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4344963-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0019787-A2 | 2-Phenylalken-1-yl-cyclopropane-carboxylic acid esters, process for their preparation and their use as insecticides and acaricides; intermediates in their preparation | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |