Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046347 | 0.86 | NR3C1 (0.62) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL11045054 | 0.85 | CRBN (0.62) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| Iodide SCHEMBL11041065 | 0.85 | NR3C1 (0.61) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL7287200 | 0.84 | CRBN (0.60) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL11042649 | 0.84 | CRBN (0.61) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL11044555 | 0.84 | KCNH2 (0.60) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL11044078 | 0.84 | NR3C1 (0.57) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL7286616 | 0.83 | CRBN (0.59) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL7319943 | 0.83 | NR3C1 (0.66) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL7269908 | 0.82 | SLC6A4 (0.78) | CRBNNR3C1PGRSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |