Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | OGT | O15294 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341674 | 0.90 | ALDH1A1 (0.53) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| SCHEMBL11046347 | 0.90 | NR3C1 (0.62) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| Hydrochloric Acid SCHEMBL11044714 | 0.89 | NR3C1 (0.52) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| Hydrochloric Acid SCHEMBL11041427 | 0.89 | NR3C1 (0.52) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| Iodide SCHEMBL11041065 | 0.88 | NR3C1 (0.61) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| Hydrochloric Acid SCHEMBL7348598 | 0.88 | ALDH1A1 (0.51) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| SCHEMBL11042243 | 0.88 | ALDH1A1 (0.61) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| SCHEMBL11044792 | 0.88 | NR3C1 (0.52) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| SCHEMBL11044078 | 0.87 | NR3C1 (0.57) | KCNH2NR3C1PGRSLC6A4PDE3B | |
| SCHEMBL11045054 | 0.87 | CRBN (0.62) | KCNH2NR3C1PGRSLC6A4PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |