SCHEMBL11043973

SCHEMBL11043973

CC(N)C(N)(CCCN)CCCN

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
KIF11 P52732 1/20 0.30
FDPS P14324 1/20 0.30
PDE3A Q14432 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL816714 0.83 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9508445 0.79 OPRM1 (0.40) LMNAFDPS
SCHEMBL8071809 0.75 OPRM1 (0.42) ALDH1A1FDPS
SCHEMBL15668489 0.75 ODC1 (0.32) ODC1KDM4ELMNAMAPTRAB9A
SCHEMBL15573847 0.75 OPRM1 (0.42) ALDH1A1FDPS
SCHEMBL19253997 0.75 OPRM1 (0.42) ALDH1A1FDPS
SCHEMBL11792783 0.75 OPRM1 (0.42) ALDH1A1FDPS
SCHEMBL7639242 0.74 ALDH1A1 (0.32) ODC1ALDH1A1KIF11FDPSPDE3A
SCHEMBL28937419 0.73 ALDH1A1 (0.35) ODC1KDM4ELMNAMAPTRAB9A
SCHEMBL5199031 0.72 ALDH1A1 (0.35) LMNABLMALDH1A1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4425249-A LUBRICANTS STANDARD OIL COMPANY (INDIANA) (US) 1984-01-10 US disclosed
US-4425245-A LUBRICANTS STANDARD OIL COMPANY (INDIANA) (US) 1984-01-10 US disclosed
US-4242212-A POLYAMINE, FORMALDEHYDE, P-MONOALKYLPHENOL OR OXIDIZED POLYOLEFIN; LUBRICANT STANDARD OIL COMPANY (INDIANA) (US) 1980-12-30 US disclosed
US-4202784-A Tertiary carbinamine modified mannich compositions and lubricants containing same STANDARD OIL COMPANY (INDIANA) (US) 1980-05-13 US disclosed