Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054054 | 0.85 | KMT2A (0.57) | HSP90AA1CYP19A1FDPSKMT2AALDH1A1 | |
| SCHEMBL11046091 | 0.85 | KMT2A (0.57) | HSP90AA1FDPSKMT2AMEN1ALDH1A1 | |
| SCHEMBL10505552 | 0.81 | HSP90AA1 (0.45) | HSP90AA1CYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6574965 | 0.79 | HSP90AA1 (1.00) | HSP90AA1CYP19A1FDPSKMT2AMEN1 | |
| SCHEMBL9719596 | 0.79 | HSP90AA1 (0.76) | HSP90AA1CYP19A1FDPSKMT2AMEN1 | |
| SCHEMBL27575720 | 0.78 | HSP90AA1 (0.65) | HSP90AA1CYP19A1FDPSKMT2AMEN1 | |
| SCHEMBL22439746 | 0.78 | HSP90AA1 (0.57) | HSP90AA1CYP19A1FDPSKMT2AMEN1 | |
| SCHEMBL11059542 | 0.77 | KMT2A (0.46) | HSP90AA1CYP19A1FDPSKMT2AMEN1 | |
| SCHEMBL9529522 | 0.77 | HSP90AA1 (0.56) | HSP90AA1CYP19A1FDPSKMT2ALMNA | |
| SCHEMBL9530860 | 0.77 | HSP90AA1 (0.56) | HSP90AA1CYP19A1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117578-A2 | Azole-substituted alcohol derivatives | SHIONOGI & CO., LTD. (JP) | 1984-09-05 | — | — | EP | disclosed |