Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503761 | 0.90 | KDM4E (0.45) | KMT2AALDH1A1POLBGAAKDM4E | |
| SCHEMBL17099930 | 0.86 | GAA (0.58) | KMT2AALDH1A1HTTGAAALOX15 | |
| SCHEMBL11654047 | 0.86 | HPGD (0.55) | ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20524406 | 0.86 | POLB (0.62) | KMT2AALDH1A1HTTPOLBKDM4E | |
| SCHEMBL27023351 | 0.86 | MAPT (0.50) | KMT2AALDH1A1HTTPOLBGAA | |
| SCHEMBL959391 | 0.86 | ALDH1A1 (0.48) | KMT2AALDH1A1POLBGAAKDM4E | |
| SCHEMBL3787010 | 0.86 | HPGD (0.55) | ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL17099947 | 0.84 | GAA (0.56) | KMT2AALDH1A1HTTGAAALOX15 | |
| SCHEMBL5561110 | 0.82 | HDAC8 (0.62) | KMT2AALDH1A1HTTPOLBGAA | |
| SCHEMBL27021670 | 0.82 | KCNK3 (0.46) | KMT2AALDH1A1HTTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435549-A | N-Cyano amide compositions and adducts thereof | W. R. GRACE & CO. (US) | 1984-03-06 | — | — | US | disclosed |