Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654047 | 1.00 | HPGD (0.55) | HPGDSMN1; SMN2POLBTYK2NPC1 | |
| SCHEMBL11044094 | 0.86 | KMT2A (0.46) | SMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL27021670 | 0.78 | KCNK3 (0.46) | GAAKCNK3KCNK9ALDH1A1 | |
| SCHEMBL10611437 | 0.78 | HPGD (0.60) | HPGDSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL2650229 | 0.77 | POLB (0.72) | HPGDSMN1; SMN2POLBTYK2NPC1 | |
| SCHEMBL3140037 | 0.77 | HPGD (0.64) | HPGDSMN1; SMN2POLBTYK2NPC1 | |
| SCHEMBL959391 | 0.77 | ALDH1A1 (0.48) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL12503761 | 0.77 | KDM4E (0.45) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL20524406 | 0.77 | POLB (0.62) | HPGDPOLBTYK2NPC1RAB9A | |
| SCHEMBL17099930 | 0.77 | GAA (0.58) | HPGDSMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113618-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-04 | — | — | EP | disclosed |
| EP-3113618-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132313-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-09-11 | — | — | WO | disclosed |
| EP-2384322-B1 | PYRIMIDINE DERIVATIVES AND USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2014-08-27 | — | — | EP | disclosed |
| EP-2206703-A1 | Pyrimidine derivatives and use thereof for combating undesired plant growth | Bayer CropScience AG (DE) | 2010-07-14 | — | — | EP | disclosed |