Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418394 | 0.86 | AKR1C3 (0.54) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL6405694 | 0.84 | SRD5A2 (0.65) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL9315768 | 0.83 | PARP10 (0.64) | KMT2AMAPTSMN1; SMN2PARP10POLB | |
| SCHEMBL9316778 | 0.83 | PARP10 (0.64) | KMT2AMAPTSMN1; SMN2PARP10POLB | |
| SCHEMBL27338061 | 0.82 | PARP10 (0.70) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL8344284 | 0.81 | CES2 (0.68) | MEN1KMT2AMAPTTDP1CES2 | |
| Bicarbonate SCHEMBL27942180 | 0.81 | KMT2A (0.60) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL11436567 | 0.79 | CES2 (0.55) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL27504557 | 0.78 | SMN1; SMN2 (0.53) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL395026 | 0.78 | CYP1A2 (0.64) | SIRT2SIRT1SIRT3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953400-A | Polyketones and methods therefor | RAYCHEM CORPORATION (US) | 1976-04-27 | — | — | US | claimed |
| EP-0069597-B1 | PREPARING P-PHENOXY-BENZOYL COMPOUNDS | RAYCHEM CORPORATION (a California corporation) (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4474990-A | Preparing p-phenoxy benzoyl compounds | RAYCHEM CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0069597-A1 | Preparing p-phenoxy-benzoyl compounds | RAYCHEM CORPORATION (a California corporation) (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4229564-A | SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS | RAYCHEM CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4024314-A | Electrical conductor insulated by a polyketones | RAYCHEM CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3953400-A | Polyketones and methods therefor | RAYCHEM CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |