SCHEMBL9315768

SCHEMBL9315768

O=C(F)c1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.64
SRD5A2 P31213 5/20 0.62
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
LTA4H P09960 2/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
AKR1C3 P42330 1/20 0.52
PGR P06401 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 2/20 0.50
RAB9A P51151 2/20 0.50
KMT2A Q03164 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9316778 1.00 PARP10 (0.64) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL11425374 0.90 PARP10 (0.53) PARP10SRD5A2ERCC5FEN1SMN1; SMN2
SCHEMBL11044183 0.83 SIRT2 (0.51) PARP10SRD5A2AKR1C3SMN1; SMN2ALDH1A1
SCHEMBL2866068 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL4189871 0.82 PARP10 (0.69) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL1888572 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL1082112 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL6892687 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL200428 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL235530 0.82 SRD5A2 (0.88) PARP10SRD5A2ERCC5FEN1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326849-A Method for producing an aromatic poly (thio) ether ketone MITSUBISHI KASEI CORPORATION (JP) 1994-07-05 US claimed
US-5326849-A Method for producing an aromatic poly (thio) ether ketone MITSUBISHI KASEI CORPORATION (JP) 1994-07-05 US disclosed