Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916750 | 0.79 | SLC6A4 (0.36) | CASP1ACP3CNR2KDM4EKMT2A | |
| SCHEMBL15918201 | 0.78 | CASP1 (0.67) | CASP1ACP3CNR2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL11041726 | 0.78 | CES2 (0.42) | CASP1KDM4EKMT2AALDH1A1MC4R | |
| SCHEMBL12462315 | 0.78 | SLC6A4 (0.35) | ACP3CNR2KDM4EKMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL251046 | 0.78 | SLC6A4 (0.35) | CASP1ACP3CNR2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL11042289 | 0.78 | ESR1 (0.41) | CASP1ACP3KDM4ETDP1 | |
| SCHEMBL14654020 | 0.77 | TDP1 (0.32) | CASP1ACP3CNR2KDM4EKMT2A | |
| SCHEMBL7899801 | 0.77 | KDM4E (0.34) | CASP1ACP3CNR2KDM4EKMT2A | |
| SCHEMBL935993 | 0.77 | KDM4E (0.34) | CASP1ACP3CNR2KDM4EKMT2A | |
| SCHEMBL12462544 | 0.77 | KDM4E (0.34) | CASP1ACP3CNR2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |