Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MB | P02144 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026046 | 0.82 | POLB (0.51) | MTNR1AMTNR1BHPGDRECQLSMN1; SMN2 | |
| SCHEMBL11042959 | 0.82 | POLB (0.48) | MTNR1AMTNR1BSMN1; SMN2POLBPKM | |
| SCHEMBL11878187 | 0.81 | POLB (0.50) | MTNR1AMTNR1BHPGDRECQLSMN1; SMN2 | |
| SCHEMBL9773576 | 0.79 | POLB (0.50) | SMN1; SMN2POLBPKMMAOBALDH1A1 | |
| SCHEMBL31198180 | 0.77 | POLB (0.58) | HPGDSMN1; SMN2POLBPKMALDH1A1 | |
| SCHEMBL28627643 | 0.76 | EGFR (0.57) | SMN1; SMN2POLBPKMALDH1A1KMT2A | |
| SCHEMBL11515756 | 0.76 | KLF10 (0.51) | MTNR1AMTNR1BALDH1A1TNKS2CA12 | |
| SCHEMBL28629516 | 0.74 | EGFR (0.62) | HPGDRECQLSMN1; SMN2POLBPKM | |
| SCHEMBL10654883 | 0.73 | TDP1 (0.46) | SMN1; SMN2POLBPKMMAOBALDH1A1 | |
| SCHEMBL28837437 | 0.73 | POLB (0.50) | SMN1; SMN2POLBPKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984000032-A1 | AMINO-OXY-(MERCAPTO-ALKYL)-BENZENES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL PRODUCTS CONTAINING THEM | SANDOZ AG (CH) | 1984-01-05 | — | — | WO | disclosed |