Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878187 | 0.95 | POLB (0.50) | POLBPKMMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11042959 | 0.88 | POLB (0.48) | POLBPKMMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8590962 | 0.88 | TYR (0.56) | POLBPKMALDH1A1CYP1A2HPGD | |
| SCHEMBL31198180 | 0.85 | POLB (0.58) | POLBPKMALDH1A1CYP1A2HPGD | |
| SCHEMBL12719477 | 0.84 | ALDH1A1 (0.49) | POLBALDH1A1CYP1A2HPGDRECQL | |
| SCHEMBL9773576 | 0.84 | POLB (0.50) | POLBPKMALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL10888531 | 0.83 | TYR (0.55) | POLBPKMALDH1A1CYP1A2HPGD | |
| SCHEMBL11044273 | 0.82 | MTNR1A (0.45) | POLBPKMMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28627643 | 0.81 | EGFR (0.57) | POLBPKMALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL7381634 | 0.81 | POLB (0.48) | POLBALDH1A1HPGDRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725636-A | Soluble polyimide containing ether bond and tertiary butyl and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2015-06-24 | — | — | CN | disclosed |