Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL31730241 | 1.00 | DNM1 (0.68) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL5673150 | 1.00 | DNM1 (0.68) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1032589 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1036903 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL17839027 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL7929478 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL7607588 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL372367 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1032903 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL7611733 | 0.98 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451680-A | RUTHENIUM COMPOUND, BIDENTATE OR MULTIDENTATE PHOSPHINE, PHOSPHONIUM COMPOUND | TEXACO INC. (US) | 1984-05-29 | — | — | US | claimed |